James Handy

A large spider from the jungles of South America is accidentally transported in a crate with a dead body to America where it mates with a local spider. Soon after, the residents of a small California town disappear as the result of spider bites from the deadly spider offspring. It's up to a couple of doctors with the help of an insect exterminator to annihilate these eight legged freaks.

Frank Galvin is a down-on-his-luck lawyer and reduced to drinking and ambulance chasing, when a former associate reminds him of his obligations in a medical malpractice suit by serving it to Galvin on a silver platter...

James Belushi is a narcotics cop deemed too crazy to team with anybody, and so is partnered with a headstrong German shepherd.